AskDefine | Define ossify

Dictionary Definition



1 become bony; "The tissue ossified"
2 make rigid and set into a conventional pattern; "rigidify the training schedule"; "ossified teaching methods"; "slogans petrify our thinking" [syn: rigidify, petrify]
3 cause to become hard and bony; "The disease ossified the tissue" [also: ossified]

User Contributed Dictionary



  1. To form into bone; to change from a soft animal substance into bone, as by the deposition of lime salts.
  2. To become inflexible in one's habits or opinions.

Extensive Definition

Ossification is the process of bone formation, in which connective tissues, such as cartilage are turned to bone or bone-like tissue. The ossified tissue is invaginated with blood vessels. These blood vessels bring minerals like calcium and deposit it in the ossifying tissue. Bone formation is a dynamic process, with cells called osteoblasts depositing minerals, and osteoclasts removing bone. This process, termed bone remodeling continues throughout life.

Types of ossification


Several hypotheses have been proposed for how bone evolved as a structural element in vertebrates. One popular idea is that bone developed from tissues that evolved to store minerals. In this model, minerals such as calcium were stored in cartilage, and that bone was an exaptation from this ossified cartilage. However, other possibilities include bony tissue evolving as an osmotic barrier, or as a protective structure.


ossify in Indonesian: Osifikasi
ossify in Japanese: 骨化
ossify in Swedish: Benbildning
ossify in Thai: การกลายเป็นกระดูก
ossify in Chinese: 成骨作用

Synonyms, Antonyms and Related Words

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